On April 19, 2024, a workshop and discussion were held on the topic Identification of Intelligent Specialization Domains of the Prešov Region. The aim of the workshop was to identify the key factors of innovative industry for the 21st century and related sectors, which relevant actors perceive as key for future innovation-driven economic growth in the context of digital transformation and sustainability. The workshop was attended by members of FFAMM FMB UP, members of the project KEGA no. 001PU-4/2022, doc. Ing. Sylvia Jenčová, PhD., doc. PhDr. Petra Vašaničová, PhD., Ing. Mária Matijová, PhD., Mgr. Martina Košíková, PhD. Mgr. Marta Miškufová, PhD., as well as prof. Ing. Peter Adamišin, PhD., doc. Ing. Martin Rovňák, PhD., several important actors from the academic environment, the business environment and the Research and Innovation Authority.